Lorenzo Musetti did not win the 2025 Chengdu Open, as he was defeated in the final by Alejandro Tabilo. Musetti entered the tournament as the top seed and had a strong run to the championship match, defeating Dino Prizmic in the round of 16, Nikoloz Basilashvili in the quarterfinals, and Alexander Shevchenko in the semifinals. In the final, which took place on September 23, 2025, Tabilo won in three sets with a score of 6-3, 2-6, 7-6. Therefore, as of the requested date of September 18, 2025, the tournament was still ongoing, and Musetti ultimately finished as the runner-up.